zoom.pls_tool.run_component_eval

zoom.pls_tool.run_component_eval(expression: pandas.DataFrame, SBP: pandas.DataFrame, ncomps: numpy.ndarray | list, cv: int, seed: int, repeats: int) → int[source]

Evaluate optimal component for PLS-R through cross-validation strategy.

Parameters:

  • expression (pd.DataFrame) – AHBA gene expression matrix.

  • SBP (pd.DataFrame) – One-dimensional data frame of spatial brain phenotype.

  • ncomps (np.ndarray or list) – Optimal component number candidates.

  • cv (int) – Number of folds in cross-validation.

  • seed (int) – Random seed to control the dataset split.

  • repeats (int) – How many times should optimal component evaluation be run?

Returns:

best_comp – The optimal component number for current PLS-R model.

Return type:

int

References

Wang, Y. et al. Spatio-molecular profiles shape the human cerebellar hierarchy along the sensorimotor-association axis. Cell Rep. 43, 113770 (2024).